GURPS

From AJS.COM

GURPS is the Generic Universal Role Playing System developed by Steve Jackson Games.

In August of 2004 (at Gen Con), GURPS introduced its 4th edition. This edition is largely compatible with 3rd edition, given a free document that defines conversion of attributes, advantages, disadvantages and skills (many of which convert with no change). However, some of the 3rd edition books such as GURPS: Vehicles are simply not usable with the new system.

Games using GURPS

Web of Truth: The Beginning - A secret conspiracies game where the players are leaders of secret organizations.
Eurora - Originally created for Hero System , a conversion is under way to 4th edition GURPS.